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Check out our latest must-read new arrivals.
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Check out our latest must-read new arrivals.
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Journal Title: Stem Cells Translational Medicine
Volume/Issue: Vol. 8, Issue: 9 (Sept 2019)
Article Title: Convergence of Cell Pharmacology and Drug Delivery
Pages: 874-879
Author: Aijaz, Ayesha; Vaninov, Natalie; Allen, Ashley; Barcia, Rita N; Parekkadan, Biju.
Database: ProQuest Health Research Premium Collection
Abstract: Future innovations focused on improvements in drug delivery using a pharmacokinetics (PK) / pharmacodynamics (PD) perspective can aid in designing a cell therapeutic product to overcome any pharmacological barriers for a given disease application. Herein, we present a perspective on the development of an ex vivo mesenchymal stromal therapeutic using a PK/PD framework and also present examples of general cell engineering techniques that implicitly influence the PK/PD curve by genetically modifying cells to regulate their in vivo duration, biodistribution, and activity.
Link: https://search.proquest.com/scholarly-journals/convergence-cell-pharmacology-drug-delivery/docview/2278362460/se-2?accountid=147682
Journal Title: CPT: Pharmacometrics & Systems Pharmacology
Volume/Issue: Vol. 8, Issue: 6 (Jun 2019)
Article Title: Quantitative Systems Pharmacology: A Regulatory Perspective on Translation
Pages: 336-339
Author: Zineh, Issam
Database: ProQuest Health Research Premium Collection
Abstract: Interest in QSP as an approach to mechanistically inform drug development has exploded in recent years. Additionally, both drug development and regulatory scientists have increasingly expressed interest in the potential for QSP to guide regulatory decisions. The extent to which QSP can routinely do either is an open question, and there have been examples of QSP facilitating key decisions and transitions in drug discovery and development.
Link: https://search.proquest.com/scholarly-journals/quantitative-systems-pharmacology-regulatory/docview/2265775295/se-2?accountid=147682
Journal Title: Molecules
Volume/Issue: Volume: 25, Issue: 33 (2020)
Article Title: Bergenia Genus: Traditional Uses, Phytochemistry and Pharmacology
Author: Bhupendra Koul, Arvind Kumar, Dhananjay Yadav, Jun-O. Jin
Database: ProQuest Health Research Premium Collection
Abstract: This review provides explicit information on the traditional uses, phytochemistry, and pharmacological significance of the genus Bergenia. The extant literature concerned was systematically collected from various databases, weblinks, blogs, books, and theses to select 174 references for detailed analysis.
Link: https://search.proquest.com/scholarly-journals/bergenia-genus-traditional-uses-phytochemistry/docview/2465897877/se-2?accountid=147682
Journal Title: Psychopharmacology
Volume/Issue: Vol. 236, Issue: 11 (Nov 2019)
Article Title: Methadone serum concentrations and influencing factors: A naturalistic observational study
Pages: 3159-3167
Author: Chalabianloo, Fatemeh; Westin, Andreas A; Skogvoll, Eirik; Bramness, Jørgen G; Spigset, Olav.
Database: ProQuest Health Research Premium Collection
Abstract: Although methadone maintenance treatment (MMT) has long been used for opioid addiction, our knowledge on its pharmacokinetics is still limited. We aimed to investigate effects of age, gender, and various co-medications on methadone serum concentration-to-dose ratio (CDR) in a naturalistic setting.
Link: https://search.proquest.com/scholarly-journals/methadone-serum-concentrations-influencing/docview/2231160774/se-2?accountid=147682
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology
Volume/Issue: Vol. 9, Issue: 5 (2019)
Article Title: A comparative study of the efficacy of cilnidipine and amlodipine used for the treatment of hypertension at tertiary health-care center
Pages: 454-458
Author :Dharapur, Preeti Mallikarjunappa; Patil, Ketan Avinash.
Database: ProQuest Health Research Premium Collection
Abstract: One of the major problems in treatment patients of hypertension (HTN) is controlling their systolic blood pressure (SBP) and diastolic BP (DBP). This study aims to study the efficacy of cilnidipine and amlodipine used for the treatment of HTN at tertiary health-care center
Link: https://search.proquest.com/scholarly-journals/comparative-study-efficacy-cilnidipine-amlodipine/docview/2250973908/se-2?accountid=147682
Journal Title: Cancer Chemotherapy and Pharmacology
Volume/Issue: Volume: 84, Issue: 1 (Jul 2019)
Article Title: Chemotherapy and cognition: comprehensive review on doxorubicin-induced chemobrain
Pages: 1-14
Author: Sara Emad El-Agamy; Amal Kamal Abdel-Aziz; Ahmed, Esmat; Azab, Samar S.
Database: ProQuest Health Research Premium Collection
Abstract: This review is intended to address the current knowledge regarding the mechanisms underlying the pathophysiology of the chemobrain phenomenon, with special focus on the antineoplastic agent ‘’doxorubicin’’, which has been shown to be implicated in strenuous central neurotoxicity despite being—almost entirely—peripherally confned.
Link: https://search.proquest.com/scholarly-journals/chemotherapy-cognition-comprehensive-review-on/docview/2204042294/se-2?accountid=147682
